44 research outputs found
An investigation of time efficiency in wavelet-based Markov parameter extraction methods
This paper investigates the time efficiency of using a wavelet transform-based method to extract the impulse response characteristics of a structural dynamic system. Traditional time domain procedures utilize the measured disturbances and response histories of a system to develop a set of auto and cross correlation functions. Through deconvolution of these functions, or matrix inversion, the Markov parameters of the system may be found. By transforming these functions into a wavelet basis, the size of the problem to be solved can be reduced as well as the computation time decreased. Fourier transforms are also used in this capacity as they may increase the time efficiency even more, but at the cost of accuracy. This paper will therefore compare the time requirements associated with a time, wavelet, and Fourier-based method of Markov parameter extraction, as well as their relative accuracy in modeling the system
Reduced order models for control of fluids using the Eigensystem Realization Algorithm
In feedback flow control, one of the challenges is to develop mathematical
models that describe the fluid physics relevant to the task at hand, while
neglecting irrelevant details of the flow in order to remain computationally
tractable. A number of techniques are presently used to develop such
reduced-order models, such as proper orthogonal decomposition (POD), and
approximate snapshot-based balanced truncation, also known as balanced POD.
Each method has its strengths and weaknesses: for instance, POD models can
behave unpredictably and perform poorly, but they can be computed directly from
experimental data; approximate balanced truncation often produces vastly
superior models to POD, but requires data from adjoint simulations, and thus
cannot be applied to experimental data.
In this paper, we show that using the Eigensystem Realization Algorithm (ERA)
\citep{JuPa-85}, one can theoretically obtain exactly the same reduced order
models as by balanced POD. Moreover, the models can be obtained directly from
experimental data, without the use of adjoint information. The algorithm can
also substantially improve computational efficiency when forming reduced-order
models from simulation data. If adjoint information is available, then balanced
POD has some advantages over ERA: for instance, it produces modes that are
useful for multiple purposes, and the method has been generalized to unstable
systems. We also present a modified ERA procedure that produces modes without
adjoint information, but for this procedure, the resulting models are not
balanced, and do not perform as well in examples. We present a detailed
comparison of the methods, and illustrate them on an example of the flow past
an inclined flat plate at a low Reynolds number.Comment: 22 pages, 7 figure
Human Fibroblast Sheet Promotes Human Pancreatic Islet Survival and Function In Vitro
In previous work, we engineered functional cell sheets using bone marrow-derived mesenchymal stem cells (BM-MSCs) to promote islet graft survival. In the present study, we hypothesized that a cell sheet using dermal fibroblasts could be an alternative to MSCs, and then we aimed to evaluate the effects of this cell sheet on the functional viability of human islets. Fibroblast sheets were fabricated using temperature-responsive culture dishes. Human islets were seeded onto fibroblast sheets. The efficacy of the fibroblast sheets was evaluated by dividing islets into three groups: the islets-alone group, the coculture with fibroblasts group, and the islet culture on fibroblast sheet group. The ultrastructure of the islets cultured on each fibroblast sheet was examined by electron microscopy. The fibroblast sheet expression of fibronectin (as a component of the extracellular matrix) was quantified by Western blotting. After 3 days of culture, islet viabilities were 70.2 ± 9.8%, 87.4 ± 5.8%, and 88.6 ± 4.5%, and survival rates were 60.3 ± 6.8%, 65.3 ± 3.0%, and 75.8 ± 5.6%, respectively. Insulin secretions in response to high-glucose stimulation were 5.1 ± 1.6, 9.4 ± 3.8, and 23.5 ± 12.4 μIU/islet, and interleukin-6 (IL-6) secretions were 3.0 ± 0.7, 5.1 ± 1.2, and 7.3 ± 1.0 ng/day, respectively. Islets were found to incorporate into the fibroblast sheets while maintaining a three-dimensional structure and well-preserved extracellular matrix. The fibroblast sheets exhibited a higher expression of fibronectin compared to fibroblasts alone. In conclusion, human dermal fibroblast sheets fabricated by tissue-engineering techniques could provide an optimal substrate for human islets, as a source of cytokines and extracellular matrix
Modélisation des flux d’ozone en forêts pour l’évaluation des risques : état et perspectives
Generalized Bilinear System Identification
A novel method is presented for identification of a bilinear system generalized to include higher-order input coupling terms. It derives from an existing method for identification of a continuous-time bilinear system. The method first generates a set of pulse responses from a constant input over a sample period for identification of the state matrix, the output matrix, and the direct transmission matrix. The method then produces another set of pulse responses with the same constant input over varying sample periods for identification of the input matrix and the coefficient matrices associated with the coupling terms between the state and the inputs. A simple example is given to illustrate the concept of the identification method